| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKU11069.1 | AKU11072.1 | AzCIB_1164 | AzCIB_1167 | Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. | Amino acid-binding ACT domain protein. | 0.581 |
| AKU11069.1 | gcvH | AzCIB_1164 | AzCIB_1165 | Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.532 |
| AKU11069.1 | gcvP | AzCIB_1164 | AzCIB_1166 | Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.493 |
| AKU11072.1 | AKU11069.1 | AzCIB_1167 | AzCIB_1164 | Amino acid-binding ACT domain protein. | Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. | 0.581 |
| AKU11072.1 | AKU11073.1 | AzCIB_1167 | AzCIB_1168 | Amino acid-binding ACT domain protein. | Amino acid carrier protein. | 0.504 |
| AKU11072.1 | AKU11077.1 | AzCIB_1167 | AzCIB_1172 | Amino acid-binding ACT domain protein. | Glycine cleavage T-protein. | 0.410 |
| AKU11072.1 | AKU11896.1 | AzCIB_1167 | AzCIB_2001 | Amino acid-binding ACT domain protein. | DNA internalization-related competence protein. | 0.406 |
| AKU11072.1 | AKU13808.1 | AzCIB_1167 | AzCIB_3915 | Amino acid-binding ACT domain protein. | Hypothetical protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein. | 0.448 |
| AKU11072.1 | gcvH | AzCIB_1167 | AzCIB_1165 | Amino acid-binding ACT domain protein. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.617 |
| AKU11072.1 | gcvP | AzCIB_1167 | AzCIB_1166 | Amino acid-binding ACT domain protein. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.859 |
| AKU11072.1 | gcvP-2 | AzCIB_1167 | AzCIB_2633 | Amino acid-binding ACT domain protein. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.576 |
| AKU11072.1 | glyA-2 | AzCIB_1167 | AzCIB_1169 | Amino acid-binding ACT domain protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.447 |
| AKU11073.1 | AKU11072.1 | AzCIB_1168 | AzCIB_1167 | Amino acid carrier protein. | Amino acid-binding ACT domain protein. | 0.504 |
| AKU11073.1 | AKU11077.1 | AzCIB_1168 | AzCIB_1172 | Amino acid carrier protein. | Glycine cleavage T-protein. | 0.467 |
| AKU11073.1 | gcvH | AzCIB_1168 | AzCIB_1165 | Amino acid carrier protein. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.441 |
| AKU11073.1 | gcvP | AzCIB_1168 | AzCIB_1166 | Amino acid carrier protein. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.526 |
| AKU11073.1 | glyA-2 | AzCIB_1168 | AzCIB_1169 | Amino acid carrier protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.665 |
| AKU11077.1 | AKU11072.1 | AzCIB_1172 | AzCIB_1167 | Glycine cleavage T-protein. | Amino acid-binding ACT domain protein. | 0.410 |
| AKU11077.1 | AKU11073.1 | AzCIB_1172 | AzCIB_1168 | Glycine cleavage T-protein. | Amino acid carrier protein. | 0.467 |
| AKU11077.1 | gcvH | AzCIB_1172 | AzCIB_1165 | Glycine cleavage T-protein. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
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