Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene co-occurrence
gene fusions
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eddPhosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (615 aa)    
Predicted Functional Partners:
AKU11167.1
4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-deoxyphosphogluconate aldolase.
 
 
 0.997
pgl
Hypothetical protein; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
 
 
 0.996
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
  
 0.968
glk
Glucokinase/transcriptional regulator, RpiR family, fusion; Belongs to the bacterial glucokinase family.
 
  
 0.797
leuC
Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
  
 0.792
AKU11166.1
Aldehyde dehydrogenase.
  
 
 0.754
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.705
AKU14053.1
Glutamate synthase.
  
  
 0.676
AKU11171.1
Transcriptional regulator, RpiR family.
 
   
 0.661
AKU13419.1
Acetolactate synthase 3 regulatory subunit.
 
 
 0.658
Your Current Organism:
Azoarcus sp. CIB
NCBI taxonomy Id: 198107
Other names: A. sp. CIB
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