close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhA-2Pyruvate dehydrogenase E1 component (alpha subunit) oxidoreductase protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (363 aa)    
Predicted Functional Partners:
AKU10921.1
Pyruvate dehydrogenase E1 component (beta subunit) oxidoreductase protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
AKU11823.1
Pyruvate dehydrogenase E1 component (beta subunit) oxidoreductase protein.
 0.999
AKU10887.1
Dihydrolipoamide dehydrogenase.
 
 0.998
AKU13751.1
Pyruvate dehydrogenase E1 component (beta subunit) oxidoreductase protein.
 0.997
AKU11824.1
Branched-chain alpha-keto acid dehydrogenase subunit E2.
 
 0.995
AKU11757.1
Dihydrolipoamide dehydrogenase.
 
 
 0.974
AKU10922.1
Pyruvate dehydrogenase E2 component.
 
 0.972
AKU12181.1
Dihydrolipoamide dehydrogenase.
  
 
 0.969
AKU10888.1
Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.960
AKU10446.1
Fused malic enzyme predicted oxidoreductase/predicted phosphotransacetylase.
  
 
 0.959
Your Current Organism:
Azoarcus sp. CIB
NCBI taxonomy Id: 198107
Other names: A. sp. CIB
Server load: low (20%) [HD]