Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKU12705.1Protein tyrosine phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (156 aa)    
Predicted Functional Partners:
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
     
 0.817
AKU12946.1
Thioredoxin; Belongs to the thioredoxin family.
  
 
 0.771
AKU11157.1
Beta-lactamase domain protein.
  
 
 0.690
AKU10041.1
Fructosamine kinase.
 
     0.682
AKU10633.1
Putative membrane-bound regulator; HflC and HflK could regulate a protease.
  
  
 0.588
AKU12707.1
Aromatic amino acid aminotransferase.
   
   0.575
AKU13436.1
Hypothetical protein.
 
  
 0.570
AKU11033.1
arsB, putative arsenical-resistance protein.
  
  
 0.548
AKU14205.1
Putative TonB-dependent receptor.
    
 
 0.468
engB
Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
  
    0.453
Your Current Organism:
Azoarcus sp. CIB
NCBI taxonomy Id: 198107
Other names: A. sp. CIB
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