Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nnrEHypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] (501 aa)    
Predicted Functional Partners:
AKU12873.1
Hydrogen dehydrogenase, alpha subunit.
   
  0.844
AKU14480.1
Formate dehydrogenase, NAD(P) reducing, beta subunit.
   
  0.844
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 
 0.838
AKU11956.1
Hypothetical protein; Belongs to the MEMO1 family.
  
 
 0.814
AKU13196.1
Hypothetical protein.
 
 
 0.791
AKU10265.1
ATP-dependent RNA helicase; Belongs to the DEAD box helicase family.
  
 0.781
AKU11164.1
ATP-independent RNA helicase; Belongs to the DEAD box helicase family.
  
 0.781
deaD
ATP-dependent RNA helicase DeaD; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
  
 0.781
AKU13218.1
ATP-dependent RNA helicase; Belongs to the DEAD box helicase family.
  
 0.781
rhlE
ATP-dependent RNA helicase; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.
  
 0.781
Your Current Organism:
Azoarcus sp. CIB
NCBI taxonomy Id: 198107
Other names: A. sp. CIB
Server load: low (24%) [HD]