close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKU12790.1Hypothetical protein. (415 aa)    
Predicted Functional Partners:
AKU12613.1
Metal dependent phosphohydrolase/3,5-cyclic-nucleotide phosphodiesterase.
 
  
 0.704
AKU10886.1
Diguanylate cyclase.
 
 
 0.539
nnrE
Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]
       0.513
AKU12542.1
Diguanylate cyclase/phosphodiesterase.
 
 
 0.507
AKU11984.1
Diguanylate cyclase; Contains PAS/PAC and GAF sensors.
 
 0.490
AKU12240.1
Complex sensory protein.
 
 
 0.490
AKU10422.1
Hypothetical protein.
 
 
 0.472
AKU10748.1
Hypothetical protein.
 
 
 0.459
AKU10216.1
Hypothetical protein.
 
   
 0.458
AKU14532.1
Putative response regulator receiver modulated diguanylate cyclase/phosphodiesterase.
 
 
 0.451
Your Current Organism:
Azoarcus sp. CIB
NCBI taxonomy Id: 198107
Other names: A. sp. CIB
Server load: low (22%) [HD]