Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKU12867.1Alpha/beta hydrolase fold. (269 aa)    
Predicted Functional Partners:
AKU12866.1
O-acetylhomoserine aminocarboxypropyltransferase.
 
   
 0.821
AKU12865.1
Hypothetical protein.
       0.679
AKU10887.1
Dihydrolipoamide dehydrogenase.
   
 0.676
AKU10916.1
AMP-dependent synthetase and ligase.
  
 
 0.613
AKU12868.1
Integral membrane protein.
       0.597
AKU12869.1
Hypothetical protein.
       0.543
AKU12025.1
Sarcosine oxidase subunit alpha; Belongs to the GcvT family.
  
 0.538
AKU12555.1
Hypothetical protein.
  
  
 0.491
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
  
 0.487
AKU11422.1
NADH:flavin oxidoreductase.
  
 0.477
Your Current Organism:
Azoarcus sp. CIB
NCBI taxonomy Id: 198107
Other names: A. sp. CIB
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