Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nadENAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (523 aa)    
Predicted Functional Partners:
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.960
nadK
Putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.952
AKU14175.1
NAD-dependent deacetylase.
    
 0.946
AKU13221.1
Pyridine nucleotide transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.936
nudC
NTP pyrophosphohydrolase; Belongs to the Nudix hydrolase family. NudC subfamily.
  
 
 0.916
AKU13222.1
Pyridine nucleotide transhydrogenase, alpha subunit.
     
 0.912
AKU13223.1
Pyridine nucleotide transhydrogenase, alpha subunit.
     
 0.912
AKU12975.1
PII-like signal transmitter protein; Belongs to the P(II) protein family.
  
  
 0.806
AKU13512.1
Chorismate mutase/prephenate dehydratase.
  
  
 0.737
AKU13297.1
Hypothetical protein.
  
 
 0.719
Your Current Organism:
Azoarcus sp. CIB
NCBI taxonomy Id: 198107
Other names: A. sp. CIB
Server load: low (12%) [HD]