| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKU10750.1 | AKU10752.1 | AzCIB_0845 | AzCIB_0847 | Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.948 |
| AKU10750.1 | AKU10757.1 | AzCIB_0845 | AzCIB_0852 | Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.971 |
| AKU10750.1 | AKU12960.1 | AzCIB_0845 | AzCIB_3067 | Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.404 |
| AKU10750.1 | AKU13330.1 | AzCIB_0845 | AzCIB_3437 | Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.918 |
| AKU10750.1 | AKU13734.1 | AzCIB_0845 | AzCIB_3841 | Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.404 |
| AKU10750.1 | eno | AzCIB_0845 | AzCIB_1974 | Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.979 |
| AKU10750.1 | fbp | AzCIB_0845 | AzCIB_0763 | Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Fructose-1,6-bisphosphatase; Belongs to the FBPase class 1 family. | 0.966 |
| AKU10750.1 | pfp | AzCIB_0845 | AzCIB_3133 | Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.963 |
| AKU10750.1 | pgi | AzCIB_0845 | AzCIB_1267 | Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.976 |
| AKU10750.1 | tal | AzCIB_0845 | AzCIB_3155 | Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. | 0.970 |
| AKU10752.1 | AKU10750.1 | AzCIB_0847 | AzCIB_0845 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | 0.948 |
| AKU10752.1 | AKU10757.1 | AzCIB_0847 | AzCIB_0852 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.936 |
| AKU10752.1 | AKU13330.1 | AzCIB_0847 | AzCIB_3437 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.909 |
| AKU10752.1 | eno | AzCIB_0847 | AzCIB_1974 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.987 |
| AKU10752.1 | pfp | AzCIB_0847 | AzCIB_3133 | Pyruvate kinase; Belongs to the pyruvate kinase family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.890 |
| AKU10752.1 | pgi | AzCIB_0847 | AzCIB_1267 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.972 |
| AKU10752.1 | tal | AzCIB_0847 | AzCIB_3155 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. | 0.879 |
| AKU10757.1 | AKU10750.1 | AzCIB_0852 | AzCIB_0845 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | 0.971 |
| AKU10757.1 | AKU10752.1 | AzCIB_0852 | AzCIB_0847 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.936 |
| AKU10757.1 | AKU13330.1 | AzCIB_0852 | AzCIB_3437 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.936 |
