close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKU13165.1Isocitrate dehydrogenase, NADP-dependent. (414 aa)    
Predicted Functional Partners:
AKU12813.1
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 0.992
AKU12812.1
Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Belongs to the aconitase/IPM isomerase family.
  
 
 0.986
AKU11759.1
2-oxoglutarate dehydrogenase E1 component.
  
 
 0.984
AKU13166.1
Isocitrate dehydrogenase, NADP-dependent; Belongs to the monomeric-type IDH family.
    
 0.954
AKU11229.1
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.943
AKU11160.1
2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
  
 
 0.937
AKU12749.1
2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
  
 
 0.937
korA2
Putative 2-oxoglutarate:ferredoxin oxidoreductase alfa subunit.
  
 
 0.937
AKU11760.1
Citrate synthase; Belongs to the citrate synthase family.
 
 
 0.930
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 
 0.924
Your Current Organism:
Azoarcus sp. CIB
NCBI taxonomy Id: 198107
Other names: A. sp. CIB
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.