AKU13172.1 protein (Azoarcus sp. CIB) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

AKU13172.1

NUDIX [(Di)nucleoside polyphosphate] hydrolase; Belongs to the Nudix hydrolase family. (140 aa)

Predicted Functional Partners:

dut

0.801

AKU13174.1

0.787

AKU13175.1

0.578

AKU13207.1

0.514

bssK

0.423

polA

0.404

Your Current Organism:

Azoarcus sp. CIB

NCBI taxonomy Id: 198107
Other names: A. sp. CIB

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKU13172.1	AKU13174.1	AzCIB_3279	AzCIB_3281	NUDIX [(Di)nucleoside polyphosphate] hydrolase; Belongs to the Nudix hydrolase family.	Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.	0.787
AKU13172.1	AKU13175.1	AzCIB_3279	AzCIB_3282	NUDIX [(Di)nucleoside polyphosphate] hydrolase; Belongs to the Nudix hydrolase family.	DNA repair protein, RadC; Belongs to the UPF0758 family.	0.578
AKU13172.1	AKU13207.1	AzCIB_3279	AzCIB_3314	NUDIX [(Di)nucleoside polyphosphate] hydrolase; Belongs to the Nudix hydrolase family.	Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.	0.514
AKU13172.1	bssK	AzCIB_3279	AzCIB_4514	NUDIX [(Di)nucleoside polyphosphate] hydrolase; Belongs to the Nudix hydrolase family.	BssK.	0.423
AKU13172.1	dut	AzCIB_3279	AzCIB_3280	NUDIX [(Di)nucleoside polyphosphate] hydrolase; Belongs to the Nudix hydrolase family.	Deoxyuridine 5-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	0.801
AKU13172.1	polA	AzCIB_3279	AzCIB_0490	NUDIX [(Di)nucleoside polyphosphate] hydrolase; Belongs to the Nudix hydrolase family.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.404
AKU13174.1	AKU13172.1	AzCIB_3281	AzCIB_3279	Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.	NUDIX [(Di)nucleoside polyphosphate] hydrolase; Belongs to the Nudix hydrolase family.	0.787
AKU13174.1	AKU13175.1	AzCIB_3281	AzCIB_3282	Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.	DNA repair protein, RadC; Belongs to the UPF0758 family.	0.699
AKU13174.1	dut	AzCIB_3281	AzCIB_3280	Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.	Deoxyuridine 5-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	0.983
AKU13175.1	AKU13172.1	AzCIB_3282	AzCIB_3279	DNA repair protein, RadC; Belongs to the UPF0758 family.	NUDIX [(Di)nucleoside polyphosphate] hydrolase; Belongs to the Nudix hydrolase family.	0.578
AKU13175.1	AKU13174.1	AzCIB_3282	AzCIB_3281	DNA repair protein, RadC; Belongs to the UPF0758 family.	Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.	0.699
AKU13175.1	dut	AzCIB_3282	AzCIB_3280	DNA repair protein, RadC; Belongs to the UPF0758 family.	Deoxyuridine 5-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	0.632
AKU13207.1	AKU13172.1	AzCIB_3314	AzCIB_3279	Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.	NUDIX [(Di)nucleoside polyphosphate] hydrolase; Belongs to the Nudix hydrolase family.	0.514
bssK	AKU13172.1	AzCIB_4514	AzCIB_3279	BssK.	NUDIX [(Di)nucleoside polyphosphate] hydrolase; Belongs to the Nudix hydrolase family.	0.423
dut	AKU13172.1	AzCIB_3280	AzCIB_3279	Deoxyuridine 5-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	NUDIX [(Di)nucleoside polyphosphate] hydrolase; Belongs to the Nudix hydrolase family.	0.801
dut	AKU13174.1	AzCIB_3280	AzCIB_3281	Deoxyuridine 5-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.	0.983
dut	AKU13175.1	AzCIB_3280	AzCIB_3282	Deoxyuridine 5-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	DNA repair protein, RadC; Belongs to the UPF0758 family.	0.632
dut	polA	AzCIB_3280	AzCIB_0490	Deoxyuridine 5-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.666
polA	AKU13172.1	AzCIB_0490	AzCIB_3279	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	NUDIX [(Di)nucleoside polyphosphate] hydrolase; Belongs to the Nudix hydrolase family.	0.404
polA	dut	AzCIB_0490	AzCIB_3280	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	Deoxyuridine 5-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	0.666