Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKU13364.1Sulfoacetaldehyde acetyltransferase; Belongs to the TPP enzyme family. (603 aa)    
Predicted Functional Partners:
AKU13359.1
FAD dependent oxidoreductase family protein.
 
  
 0.983
AKU13360.1
Hypothetical protein.
 
  
 0.978
AKU14050.1
Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.
  
 0.941
AKU13375.1
Phosphate acetyltransferase.
 
 
 0.934
AKU13419.1
Acetolactate synthase 3 regulatory subunit.
 
 0.933
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.916
AKU10323.1
NAD-dependent glutamate dehydrogenase.
     
  0.900
AKU12256.1
NAD-dependent glutamate dehydrogenase.
     
  0.900
AKU12941.1
Acetolactate synthase 1 regulatory subunit.
  
 0.897
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.781
Your Current Organism:
Azoarcus sp. CIB
NCBI taxonomy Id: 198107
Other names: A. sp. CIB
Server load: low (20%) [HD]