Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKU13543.1Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. (139 aa)    
Predicted Functional Partners:
AKU10925.1
Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family.
  
  
 
0.925
AKU10924.1
Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family.
  
  
 
0.922
clpB
ClpB ATPase dependent protease, chaperonin; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
 
 
 0.762
AKU13180.1
ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family.
 
 
 0.735
AKU13123.1
ClpV1 protein; Belongs to the ClpA/ClpB family.
 
 
 0.732
AKU12632.1
Putative phosphoribosyltransferase.
 
  
 0.592
AKU13542.1
Hypothetical protein.
       0.563
AKU13034.1
Superoxide dismutase (Fe); Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.562
grpE
Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...]
  
 
 0.545
hscA
Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
  
 
 0.538
Your Current Organism:
Azoarcus sp. CIB
NCBI taxonomy Id: 198107
Other names: A. sp. CIB
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