Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKU13622.1Glu/Leu/Phe/Val dehydrogenase dimerization region containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (361 aa)    
Predicted Functional Partners:
AKU11823.1
Pyruvate dehydrogenase E1 component (beta subunit) oxidoreductase protein.
  
 
 0.943
pdhA-2
Pyruvate dehydrogenase E1 component (alpha subunit) oxidoreductase protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.942
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.923
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
   
 
 0.911
ilvD-2
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
   
 
 0.911
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.908
leuA-2
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.908
AKU12795.1
Aminotransferase.
  
 
 0.907
AKU14053.1
Glutamate synthase.
  
 
 0.802
AKU10446.1
Fused malic enzyme predicted oxidoreductase/predicted phosphotransacetylase.
  
 
 0.615
Your Current Organism:
Azoarcus sp. CIB
NCBI taxonomy Id: 198107
Other names: A. sp. CIB
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