queF protein (Azoarcus sp. CIB) - STRING interaction network

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queF

7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). (283 aa)

Predicted Functional Partners:

queC

0.987

queE

0.919

AKU13446.1

0.906

AKU11471.1

0.795

tgt

0.777

queA

0.662

ribB

0.615

guaA

0.612

AKU09960.1

0.577

AKU13801.1

0.559

Your Current Organism:

Azoarcus sp. CIB

NCBI taxonomy Id: 198107
Other names: A. sp. CIB

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKU09960.1	queF	AzCIB_0055	AzCIB_3907	Putative iron-sulfur binding protein.	7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).	0.577
AKU11471.1	guaA	AzCIB_1570	AzCIB_1821	GTP-binding protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.716
AKU11471.1	queF	AzCIB_1570	AzCIB_3907	GTP-binding protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.	7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).	0.795
AKU13446.1	guaA	AzCIB_3553	AzCIB_1821	6-pyruvoyltetrahydropterin synthase.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.503
AKU13446.1	queA	AzCIB_3553	AzCIB_3765	6-pyruvoyltetrahydropterin synthase.	S-adenosylmethionine--tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).	0.486
AKU13446.1	queC	AzCIB_3553	AzCIB_4244	6-pyruvoyltetrahydropterin synthase.	ExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.	0.934
AKU13446.1	queE	AzCIB_3553	AzCIB_4243	6-pyruvoyltetrahydropterin synthase.	Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.	0.992
AKU13446.1	queF	AzCIB_3553	AzCIB_3907	6-pyruvoyltetrahydropterin synthase.	7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).	0.906
AKU13446.1	tgt	AzCIB_3553	AzCIB_3766	6-pyruvoyltetrahydropterin synthase.	Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]	0.518
AKU13801.1	queF	AzCIB_3908	AzCIB_3907	Hypothetical protein.	7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).	0.559
guaA	AKU11471.1	AzCIB_1821	AzCIB_1570	GMP synthase; Catalyzes the synthesis of GMP from XMP.	GTP-binding protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.	0.716
guaA	AKU13446.1	AzCIB_1821	AzCIB_3553	GMP synthase; Catalyzes the synthesis of GMP from XMP.	6-pyruvoyltetrahydropterin synthase.	0.503
guaA	queE	AzCIB_1821	AzCIB_4243	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.	0.576
guaA	queF	AzCIB_1821	AzCIB_3907	GMP synthase; Catalyzes the synthesis of GMP from XMP.	7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).	0.612
guaA	ribB	AzCIB_1821	AzCIB_0363	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	0.711
guaA	tgt	AzCIB_1821	AzCIB_3766	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]	0.777
queA	AKU13446.1	AzCIB_3765	AzCIB_3553	S-adenosylmethionine--tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).	6-pyruvoyltetrahydropterin synthase.	0.486
queA	queC	AzCIB_3765	AzCIB_4244	S-adenosylmethionine--tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).	ExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.	0.548
queA	queE	AzCIB_3765	AzCIB_4243	S-adenosylmethionine--tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).	Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.	0.473
queA	queF	AzCIB_3765	AzCIB_3907	S-adenosylmethionine--tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).	7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).	0.662