Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKU14168.1Pteridine reductase. (248 aa)    
Predicted Functional Partners:
AKU13087.1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
     
 0.902
AKU10916.1
AMP-dependent synthetase and ligase.
  
 0.800
AKU14237.1
NAD-dependent epimerase/dehydratase.
  
     0.755
ttcA
ATPase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
     
 0.691
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
 
 0.618
AKU14167.1
Hypothetical protein.
       0.575
AKU11813.1
Short chain dehydrogenase.
 
 
 0.565
AKU10322.1
Short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 0.564
AKU14170.1
Hypothetical protein.
   
 0.548
AKU11367.1
Short-chain dehydrogenase of unknown substrate specificity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
0.538
Your Current Organism:
Azoarcus sp. CIB
NCBI taxonomy Id: 198107
Other names: A. sp. CIB
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.