Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hypAHydrogenase nickel inorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (113 aa)    
Predicted Functional Partners:
AKU14592.1
Hydrogenase accessory protein.
 
 0.997
AKU14594.1
Hypothetical protein.
 
 
 0.983
AKU14591.1
Hydrogenase maturation protein.
 
   
 0.967
AKU14590.1
Hydrogenase assembly chaperon.
 
  
 0.940
AKU14589.1
Hydrogenase expression/formation protein; Belongs to the HypD family.
 
  
 0.939
AKU14588.1
Hydrogenase expression/formation protein.
 
  
 0.934
AKU13333.1
Subunit of formate hydrogenlyase-like membrane complex, related to large subunit of hydrogenase.
  
 
 0.764
AKU12870.1
Nickel-dependent hydrogenase large subunit/hydrogen dehydrogenase, beta subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
  
 0.692
AKU14587.1
Putative formyltransferase; Belongs to the enoyl-CoA hydratase/isomerase family.
 
    0.527
AKU12780.1
Pyruvate oxidoreductase.
     
 0.513
Your Current Organism:
Azoarcus sp. CIB
NCBI taxonomy Id: 198107
Other names: A. sp. CIB
Server load: low (20%) [HD]