hemE protein (Azoarcus sp. CIB) - STRING interaction network

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hemE

Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (356 aa)

Predicted Functional Partners:

hemC

0.986

hemF

0.970

AKU12984.1

0.958

AKU13500.1

0.949

AKU10697.1

0.945

hemH

0.931

AKU10644.1

0.917

AKU10698.1

0.911

AKU13723.1

0.892

coaE

0.824

Your Current Organism:

Azoarcus sp. CIB

NCBI taxonomy Id: 198107
Other names: A. sp. CIB

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKU10644.1	AKU10697.1	AzCIB_0739	AzCIB_0792	uroporphyrin-III C-methyltransferase.	Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	0.948
AKU10644.1	AKU10698.1	AzCIB_0739	AzCIB_0793	uroporphyrin-III C-methyltransferase.	uroporphyrin-III C-methyltransferase.	0.904
AKU10644.1	AKU13500.1	AzCIB_0739	AzCIB_3607	uroporphyrin-III C-methyltransferase.	uroporphyrinogen-III methylase siroheme synthase; Belongs to the precorrin methyltransferase family.	0.953
AKU10644.1	hemC	AzCIB_0739	AzCIB_0791	uroporphyrin-III C-methyltransferase.	Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.	0.929
AKU10644.1	hemE	AzCIB_0739	AzCIB_4711	uroporphyrin-III C-methyltransferase.	Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.	0.917
AKU10697.1	AKU10644.1	AzCIB_0792	AzCIB_0739	Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	uroporphyrin-III C-methyltransferase.	0.948
AKU10697.1	AKU10698.1	AzCIB_0792	AzCIB_0793	Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	uroporphyrin-III C-methyltransferase.	0.994
AKU10697.1	AKU13500.1	AzCIB_0792	AzCIB_3607	Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	uroporphyrinogen-III methylase siroheme synthase; Belongs to the precorrin methyltransferase family.	0.974
AKU10697.1	AKU13723.1	AzCIB_0792	AzCIB_3830	Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	Hypothetical protein.	0.492
AKU10697.1	coaE	AzCIB_0792	AzCIB_0570	Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	0.445
AKU10697.1	hemC	AzCIB_0792	AzCIB_0791	Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.	0.998
AKU10697.1	hemE	AzCIB_0792	AzCIB_4711	Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.	0.945
AKU10697.1	hemF	AzCIB_0792	AzCIB_0795	Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.	0.449
AKU10697.1	hemH	AzCIB_0792	AzCIB_3017	Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.	0.506
AKU10698.1	AKU10644.1	AzCIB_0793	AzCIB_0739	uroporphyrin-III C-methyltransferase.	uroporphyrin-III C-methyltransferase.	0.904
AKU10698.1	AKU10697.1	AzCIB_0793	AzCIB_0792	uroporphyrin-III C-methyltransferase.	Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	0.994
AKU10698.1	AKU13500.1	AzCIB_0793	AzCIB_3607	uroporphyrin-III C-methyltransferase.	uroporphyrinogen-III methylase siroheme synthase; Belongs to the precorrin methyltransferase family.	0.910
AKU10698.1	hemC	AzCIB_0793	AzCIB_0791	uroporphyrin-III C-methyltransferase.	Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.	0.870
AKU10698.1	hemE	AzCIB_0793	AzCIB_4711	uroporphyrin-III C-methyltransferase.	Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.	0.911
AKU12984.1	hemC	AzCIB_3091	AzCIB_0791	Oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family.	Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.	0.492