STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SF0283Conserved hypothetical protein; Code: S; COG: COG1690. (347 aa)    
Predicted Functional Partners:
yhgJ
RNA 3'-terminal phosphate cyclase (ATP); Similar to Escherichia coli K12 positive regulator of mal regulon gi: 2367223 (902 aa). BLAST with identity of 99% in 894 aa. This CDS contains an in-frame stop codon. The sequence has been checked and is believed to be correct.
 
  
 0.843
prfH
Probable peptide chain release factor; Code: J; COG: COG1186.
 
  
 0.822
rtcR
Putative 2-component regulator; Code: O; COG: COG1221.
 
   
 0.711
pntA
Pyridine nucleotide transhydrogenase, alpha subunit; Code: C; COG: COG3288.
 
      0.666
pntB
Pyridine nucleotide transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
 
      0.664
yjiI
Conserved hypothetical protein; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.
 
   
 0.630
yehP
Conserved hypothetical protein.
  
     0.592
yehL
Conserved hypothetical protein; Code: R; COG: COG0714.
  
     0.571
SF1807
Hypothetical protein; Code: I; COG: COG0671.
  
    0.478
yehM
Conserved hypothetical protein.
 
     0.465
Your Current Organism:
Shigella flexneri
NCBI taxonomy Id: 198214
Other names: S. flexneri 2a str. 301, Shigella flexneri 2a str. 301, Shigella flexneri serotype 2a str. 301
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.