STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ybaTPutative amino acid/amine transport protein; Code: E; COG: COG0531. (430 aa)    
Predicted Functional Partners:
ybaS
Putative glutaminase; Code: E; COG: COG2066; Belongs to the glutaminase family.
  
  
 0.983
hdeD
Conserved hypothetical protein; Code: S; COG: COG3247.
  
  
 0.779
yrbH
Putative isomerase; Involved in the biosynthesis of 3-deoxy-D-manno-octulosonate (KDO), a unique 8-carbon sugar component of lipopolysaccharides (LPSs). Catalyzes the reversible aldol-ketol isomerization between D-ribulose 5-phosphate (Ru5P) and D-arabinose 5-phosphate (A5P) (By similarity).
     
 0.724
treC
Trehalase 6-P hydrolase; Code: G; COG: COG0366.
    
 0.635
gadC_1
Putative amino acid antiporter; Code: E; COG: COG0531.
  
  
 0.634
xasA
Acid sensitivity protein, putative transporter; Involved in glutamate-dependent acid resistance. Imports glutamate inside the cell while simultaneously exporting to the periplasm the GABA produced by GadA and GadB. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria (By similarity); Belongs to the amino acid-polyamine-organocation (APC) superfami [...]
  
  
 0.609
speD
S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
      
 0.581
yegP
Conserved hypothetical protein; Code: S; COG: COG3422; Belongs to the UPF0339 family. Duplicated subfamily.
  
  
 0.521
ybaR
Putative ATPase; Code: P; COG: COG2217.
     
 0.520
SF2551
Putative outer membrane lipoprotein.
  
     0.509
Your Current Organism:
Shigella flexneri
NCBI taxonomy Id: 198214
Other names: S. flexneri 2a str. 301, Shigella flexneri 2a str. 301, Shigella flexneri serotype 2a str. 301
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.