STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydfIPutative oxidoreductase; Code: G; COG: COG0246. (486 aa)    
Predicted Functional Partners:
mtlA
PTS system, mannitol-specific enzyme IIABC components; Code: C; COG: COG2213.
  
  
 0.945
proP_2
Low-affinity transport protein; Code: GEPR; COG: COG0477; proline permease II-like protein.
     
 0.591
fruB
PTS system, fructose-specific IIA/fpr component; Code: GT; COG: COG1762.
  
  
 0.591
uxuA
Mannonate hydrolase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family.
 
  
 0.542
kdgK
Ketodeoxygluconokinase; Code: G; COG: COG0524.
 
     0.476
uxaC
Uronate isomerase; Code: G; COG: COG1904.
 
  
 0.469
uxaA
Altronate hydrolase; Code: G; COG: COG2721.
 
  
 0.443
ydfH
Conserved hypothetical protein; Code: K; COG: COG1802.
     0.438
hrsA
Protein modification enzyme.
  
  
 0.413
fryA
Phosphoenolpyruvate-protein phosphotransferase; Multifunctional protein that includes general (non sugar- specific) and sugar-specific components of the phosphoenolpyruvate- dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FryABC PTS system is involved in fructose transport.
  
  
 0.405
Your Current Organism:
Shigella flexneri
NCBI taxonomy Id: 198214
Other names: S. flexneri 2a str. 301, Shigella flexneri 2a str. 301, Shigella flexneri serotype 2a str. 301
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.