SF1631 protein (Shigella flexneri) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SF1631

Putative transporter; Code: R; COG: COG1823. (348 aa)

Predicted Functional Partners:

cysJ

0.517

yciW

0.495

cysC

0.487

SF1630

0.479

rstB

0.456

Your Current Organism:

Shigella flexneri

NCBI taxonomy Id: 198214
Other names: S. flexneri 2a str. 301, Shigella flexneri 2a str. 301, Shigella flexneri serotype 2a str. 301

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SF1630	SF1631	SF1630	SF1631	Hypothetical protein.	Putative transporter; Code: R; COG: COG1823.	0.479
SF1631	SF1630	SF1631	SF1630	Putative transporter; Code: R; COG: COG1823.	Hypothetical protein.	0.479
SF1631	cysC	SF1631	SF2773	Putative transporter; Code: R; COG: COG1823.	Adenosine 5-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate.	0.487
SF1631	cysJ	SF1631	SF2780	Putative transporter; Code: R; COG: COG1823.	Sulfite reductase (NADPH), flavoprotein beta subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.517
SF1631	rstB	SF1631	SF1632	Putative transporter; Code: R; COG: COG1823.	Sensor histidine protein kinase, RstA regulator; Code: T; COG: COG0642.	0.456
SF1631	yciW	SF1631	SF1292	Putative transporter; Code: R; COG: COG1823.	Putative oxidoreductase.	0.495
cysC	SF1631	SF2773	SF1631	Adenosine 5-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate.	Putative transporter; Code: R; COG: COG1823.	0.487
cysC	cysJ	SF2773	SF2780	Adenosine 5-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate.	Sulfite reductase (NADPH), flavoprotein beta subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.951
cysC	yciW	SF2773	SF1292	Adenosine 5-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate.	Putative oxidoreductase.	0.731
cysJ	SF1631	SF2780	SF1631	Sulfite reductase (NADPH), flavoprotein beta subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	Putative transporter; Code: R; COG: COG1823.	0.517
cysJ	cysC	SF2780	SF2773	Sulfite reductase (NADPH), flavoprotein beta subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	Adenosine 5-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate.	0.951
cysJ	yciW	SF2780	SF1292	Sulfite reductase (NADPH), flavoprotein beta subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	Putative oxidoreductase.	0.912
rstB	SF1631	SF1632	SF1631	Sensor histidine protein kinase, RstA regulator; Code: T; COG: COG0642.	Putative transporter; Code: R; COG: COG1823.	0.456
yciW	SF1631	SF1292	SF1631	Putative oxidoreductase.	Putative transporter; Code: R; COG: COG1823.	0.495
yciW	cysC	SF1292	SF2773	Putative oxidoreductase.	Adenosine 5-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate.	0.731
yciW	cysJ	SF1292	SF2780	Putative oxidoreductase.	Sulfite reductase (NADPH), flavoprotein beta subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.912