STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfeOConserved hypothetical protein; Code: P; COG: COG0038. (418 aa)    
Predicted Functional Partners:
yceC
Conserved hypothetical protein; Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RluA family.
     
 0.806
eutS
Conserved hypothetical protein; May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place; Belongs to the EutS/PduU family.
      
 0.710
ydcK
Conserved hypothetical protein; Code: M; COG: COG1044.
  
     0.709
yjjQ
Putative regulator; Code: TK; COG: COG2197.
  
    0.702
ybhC
Putative pectinesterase.
  
     0.687
SF1892
Putative tail component of prophage CP-933K.
  
     0.601
aphA
Diadenosine tetraphosphatase; Dephosphorylates several organic phosphate monoesters. Also has a phosphotransferase activity catalyzing the transfer of low-energy phosphate groups from organic phosphate monoesters to free hydroxyl groups of various organic compounds (By similarity).
  
     0.599
SF0710
Putative tail component of prophage CP-933K.
  
     0.593
csgB
Minor curlin subunit precursor.
 
     0.589
abc
ATP-binding component of a transporter; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
      
 0.580
Your Current Organism:
Shigella flexneri
NCBI taxonomy Id: 198214
Other names: S. flexneri 2a str. 301, Shigella flexneri 2a str. 301, Shigella flexneri serotype 2a str. 301
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.