node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bglF | malX | SF3733 | SF1645 | PTS system beta-glucosides, enzyme II, cryptic. | Phosphotransferase system enzyme II; Code: G; COG: COG1263. | 0.863 |
bglF | murP | SF3733 | SF2483 | PTS system beta-glucosides, enzyme II, cryptic. | Putative PTS enzyme II; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P. Is also able to take up anhydro-N-acetylmuramic acid (anhMurNAc), but cannot phosphorylate the carbon 6, probably because of the 1,6-anhydro ring. | 0.856 |
bglF | nagE | SF3733 | SF0614 | PTS system beta-glucosides, enzyme II, cryptic. | N-acetylglucosamine-specific enzyme IIABC. | 0.978 |
bglF | ptsG | SF3733 | SF1105 | PTS system beta-glucosides, enzyme II, cryptic. | Glucose-specific IIBC component; Code: G; COG: COG1263. | 0.931 |
bglF | treB | SF3733 | SF4250 | PTS system beta-glucosides, enzyme II, cryptic. | PTS system enzyme II; Code: G; COG: COG1263. | 0.857 |
bglF | yfeT | SF3733 | SF2482 | PTS system beta-glucosides, enzyme II, cryptic. | Conserved hypothetical protein; Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6- phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator. | 0.510 |
bglF | yfeU | SF3733 | SF2481 | PTS system beta-glucosides, enzyme II, cryptic. | Putative regulator; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily. | 0.533 |
ftsW | murP | SF0086 | SF2483 | Membrane protein; Code: D; COG: COG0772. | Putative PTS enzyme II; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P. Is also able to take up anhydro-N-acetylmuramic acid (anhMurNAc), but cannot phosphorylate the carbon 6, probably because of the 1,6-anhydro ring. | 0.718 |
ftsW | yfeT | SF0086 | SF2482 | Membrane protein; Code: D; COG: COG0772. | Conserved hypothetical protein; Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6- phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator. | 0.718 |
ftsW | yfeU | SF0086 | SF2481 | Membrane protein; Code: D; COG: COG0772. | Putative regulator; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily. | 0.436 |
malX | bglF | SF1645 | SF3733 | Phosphotransferase system enzyme II; Code: G; COG: COG1263. | PTS system beta-glucosides, enzyme II, cryptic. | 0.863 |
malX | murP | SF1645 | SF2483 | Phosphotransferase system enzyme II; Code: G; COG: COG1263. | Putative PTS enzyme II; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P. Is also able to take up anhydro-N-acetylmuramic acid (anhMurNAc), but cannot phosphorylate the carbon 6, probably because of the 1,6-anhydro ring. | 0.645 |
malX | nagE | SF1645 | SF0614 | Phosphotransferase system enzyme II; Code: G; COG: COG1263. | N-acetylglucosamine-specific enzyme IIABC. | 0.845 |
malX | ptsG | SF1645 | SF1105 | Phosphotransferase system enzyme II; Code: G; COG: COG1263. | Glucose-specific IIBC component; Code: G; COG: COG1263. | 0.929 |
malX | treB | SF1645 | SF4250 | Phosphotransferase system enzyme II; Code: G; COG: COG1263. | PTS system enzyme II; Code: G; COG: COG1263. | 0.564 |
malX | yfeT | SF1645 | SF2482 | Phosphotransferase system enzyme II; Code: G; COG: COG1263. | Conserved hypothetical protein; Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6- phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator. | 0.430 |
malX | yfeU | SF1645 | SF2481 | Phosphotransferase system enzyme II; Code: G; COG: COG1263. | Putative regulator; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily. | 0.475 |
murP | bglF | SF2483 | SF3733 | Putative PTS enzyme II; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P. Is also able to take up anhydro-N-acetylmuramic acid (anhMurNAc), but cannot phosphorylate the carbon 6, probably because of the 1,6-anhydro ring. | PTS system beta-glucosides, enzyme II, cryptic. | 0.856 |
murP | ftsW | SF2483 | SF0086 | Putative PTS enzyme II; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P. Is also able to take up anhydro-N-acetylmuramic acid (anhMurNAc), but cannot phosphorylate the carbon 6, probably because of the 1,6-anhydro ring. | Membrane protein; Code: D; COG: COG0772. | 0.718 |
murP | malX | SF2483 | SF1645 | Putative PTS enzyme II; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P. Is also able to take up anhydro-N-acetylmuramic acid (anhMurNAc), but cannot phosphorylate the carbon 6, probably because of the 1,6-anhydro ring. | Phosphotransferase system enzyme II; Code: G; COG: COG1263. | 0.645 |