STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yffGPutative oxidoreductase, Fe-S subunit; Code: ER; COG: COG0493. (659 aa)    
Predicted Functional Partners:
gltB
Glutamate synthase, large subunit.
 
 0.999
ydbK
Putative oxidoreductase, Fe-S subunit.
  
 
 0.835
SF2530
Large subunit of hydrogenase 3.
  
 
 0.806
SF2531
Large subunit of hydrogenase 3.
  
 
 0.806
hycE
Large subunit of hydrogenase 3 (part of FHL complex); Code: C; COG: COG3261.
  
 
 0.806
hcr
Putative enzyme; Code: C; COG: COG1018.
   
 0.794
yeaX
Putative diogenase beta subunit; Code: C; COG: COG1018.
   
 0.794
nuoF
NADH dehydrogenase I chain F; Code: C; COG: COG1894.
 
  
 0.722
ycbX
Conserved hypothetical protein; Code: R; COG: COG3217.
   
 0.673
yffH
Conserved hypothetical protein; Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP- mannose as its preferred substrate, yielding GMP and mannose-1- phosphate.
       0.625
Your Current Organism:
Shigella flexneri
NCBI taxonomy Id: 198214
Other names: S. flexneri 2a str. 301, Shigella flexneri 2a str. 301, Shigella flexneri serotype 2a str. 301
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.