STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SF2917Putative ATP-binding protein of ABC transport system; Code: P; COG: COG1122. (225 aa)    
Predicted Functional Partners:
ecfA1
ABC transporter ATP-binding protein; Similar to Escherichia coli O157:H7 EDL933 conserved hypothetical protein ref: NP_289497.1 (235 aa). BLAST with identity of 97% in 236 aa. This CDS contains an in-frame stop codon. The sequence has been checked and is believed to be correct.
  
 
0.990
cysN
ATP-sulfurylase (ATP:sulfate adenylyltransferase), subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
 
  
 0.920
cysU
Sulfate/thiosulfate transporter subunit; Similar to Escherichia coli K12 sulfate transport system permease W protein gi: 1788762 (150 aa). BLAST with identity of 95% in 149 aa. This CDS contains an in-frame stop codon. The sequence has been checked and is believed to be correct.
  
  
 0.908
cysI
Sulfite reductase, alpha subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
  
 0.906
cysC
Adenosine 5-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate.
  
  
 0.903
sbp
Periplasmic sulfate-binding protein; This protein specifically binds sulfate and is involved in its transmembrane transport; Belongs to the prokaryotic sulfate-binding protein family.
  
  
 0.903
yciW
Putative oxidoreductase.
   
    0.898
cysJ
Sulfite reductase (NADPH), flavoprotein beta subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
  
  
 0.875
cysP
Thiosulfate binding protein; Code: P; COG: COG1613.
  
  
 0.834
modB
Molybdate transport permease protein; Code: P; COG: COG0555.
  
  
 0.773
Your Current Organism:
Shigella flexneri
NCBI taxonomy Id: 198214
Other names: S. flexneri 2a str. 301, Shigella flexneri 2a str. 301, Shigella flexneri serotype 2a str. 301
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.