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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
set1BShet1B. (61 aa)    
Predicted Functional Partners:
set1A
Shet1A.
      
 0.818
srlE
Similar to Escherichia coli K12 PTS system, glucitol/sorbitol-specific IIC component, one of two gi: 1789054 (187 aa). BLAST with identity of 92% in 131 aa. This CDS ontains frameshift. The sequence has been checked and is believed to be correct.
      
 0.636
SF3004
Hypothetical protein.
      
 0.636
yaaW
Putative oxidoreductase.
      
 0.501
iutA
Putative ferric siderophore receptor; Code: P; COG: COG1629.
      
 0.440
Your Current Organism:
Shigella flexneri
NCBI taxonomy Id: 198214
Other names: S. flexneri 2a str. 301, Shigella flexneri 2a str. 301, Shigella flexneri serotype 2a str. 301
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