STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dacBD-alanyl-D-alanine carboxypeptidase, fraction B, penicillin-binding protein 4; Code: M; COG: COG2027. (477 aa)    
Predicted Functional Partners:
dacA
D-alanyl-D-alanine carboxypeptidase, fraction A; Code: M; COG: COG1686; Belongs to the peptidase S11 family.
     
 0.927
SF0789
Putative D-alanyl-D-alanine carboxypeptidase, fraction A; Code: M; COG: COG1686.
     
 0.909
SF0792
Putative D-alanyl-D-alanine carboxypeptidase, fraction A; penicillin-binding protein 5.
     
 0.909
LdcA
Conserved hypothetical protein; Code: S; COG: COG1619.
 
   
 0.854
mrcA
Peptidoglycan synthetase, penicillin-binding protein 1A; Code: M; COG: COG0744.
  
   
 0.811
yaiH
Putative enzyme; Code: M; COG: COG1680.
  
   
 0.800
pbpG
Penicillin-binding protein 7; Cell wall formation. May play a specialized role in remodeling the cell wall. Specifically hydrolyzes the DD- diaminopimelate-alanine bonds in high-molecular-mass murein sacculi (By similarity); Belongs to the peptidase S11 family.
      
 0.749
ybiS
Conserved hypothetical protein; Code: S; COG: COG1376.
      
 0.739
erfK
Conserved hypothetical protein; Code: S; COG: COG1376.
      
 0.739
emrE
Resistance protein; Code: P; COG: COG2076.
     
 0.729
Your Current Organism:
Shigella flexneri
NCBI taxonomy Id: 198214
Other names: S. flexneri 2a str. 301, Shigella flexneri 2a str. 301, Shigella flexneri serotype 2a str. 301
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.