STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nikBTransport of nickel, membrane protein; Code: EP; COG: COG0601. (314 aa)    
Predicted Functional Partners:
nikA
Periplasmic binding protein for nickel; Code: EP; COG: COG0747.
 0.999
nikC
Transport of nickel, membrane protein; Code: EP; COG: COG1173.
 
 0.999
nikD
ATP-binding protein of nickel transport system; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.
 
 0.999
nikE
ATP-binding protein of nickel transport system; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.
 
 0.999
gsiD
Putative transport system permease protein; Part of the ABC transporter complex GsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane.
  
 0.877
dppC
Dipeptide transport system permease protein 2; Code: EP; COG: COG1173.
  
 0.877
oppC
Oligopeptide transport permease protein; Code: EP; COG: COG1173.
  
 0.874
gsiA_2
ABC transporter ATP-binding protein; Similar to Escherichia coli K12 putative transport protein gi: 1787760 (299 aa). BLAST with identity of 98% in 299 aa. This CDS ontains frameshift. The sequence has been checked and is believed to be correct; Belongs to the ABC transporter superfamily.
 
 
 0.857
dppD
Putative ATP-binding component of dipeptide transport system; Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system (By similarity); Belongs to the ABC transporter superfamily.
 
 0.854
oppD
ATP-binding protein of oligopeptide ABC transport system; Code: EP; COG: COG0444; Belongs to the ABC transporter superfamily.
 
 0.846
Your Current Organism:
Shigella flexneri
NCBI taxonomy Id: 198214
Other names: S. flexneri 2a str. 301, Shigella flexneri 2a str. 301, Shigella flexneri serotype 2a str. 301
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