STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yhiIPutative membrane protein; Code: Q; COG: COG0845. (355 aa)    
Predicted Functional Partners:
yhiH
Putative ATP-binding component of a transport system.
 
  
 0.971
yhhJ
Putative transporter; Code: R; COG: COG0842.
 
  
 0.967
ybjZ
Putative ATP-binding component of a transport system; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.850
ybhF
Putative ATP-binding component of a transport system; Part of the ABC transporter complex YbhFSR that could be involved in efflux of cefoperazone. Probably responsible for energy coupling to the transport system.
 
  
 0.749
ybhS
Conserved hypothetical protein; Code: R; COG: COG0842.
 
  
 0.743
ytfL
Putative transport protein; Code: R; COG: COG1253.
     
 0.734
insA-7
IS1 ORF1; Code: L; COG: COG3677.
      
 0.731
yqgB
Conserved hypothetical protein.
      
 0.719
sugE
Suppresser of groEL; Guanidinium ion exporter. Couples guanidinium export to the proton motive force, exchanging one guanidinium ion for two protons. Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Gdx/SugE subfamily.
   
  
 0.719
yhfK
Conserved hypothetical protein; Code: S; COG: COG1289.
  
  
 0.717
Your Current Organism:
Shigella flexneri
NCBI taxonomy Id: 198214
Other names: S. flexneri 2a str. 301, Shigella flexneri 2a str. 301, Shigella flexneri serotype 2a str. 301
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.