STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
yifAConserved hypothetical protein; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon. (279 aa)    
Predicted Functional Partners:
yeiE
Putative LYSR-type transcriptional regulator; Code: K; COG: COG0583; Belongs to the LysR transcriptional regulatory family.
  
     0.747
yhcS
Putative LYSR-type transcriptional regulator; Code: K; COG: COG0583.
  
     0.724
nac
Nitrogen assimilation control protein; Code: K; COG: COG0583; Belongs to the LysR transcriptional regulatory family.
  
     0.720
lysR
Positive regulator for lysine; Code: K; COG: COG0583.
  
     0.716
yifE
Conserved hypothetical protein; Code: S; COG: COG3085; Belongs to the UPF0438 family.
 
   
 0.618
yhjC
Putative transcriptional regulator LYSR-type; Code: K; COG: COG0583; Belongs to the LysR transcriptional regulatory family.
  
     0.591
ygiP
Putative LYSR-type transcriptional regulator; Code: K; COG: COG0583; Belongs to the LysR transcriptional regulatory family.
  
     0.544
metR
Regulator for metE and metH; Control of the last step in methionine biosynthesis; MetR is a positive activator of the metA, metE and metH genes. It is also a negative regulator of its own expression (By similarity). Belongs to the LysR transcriptional regulatory family.
  
     0.530
flgN
Flagella synthesis protein FlgN; Code: N; COG: COG3418.
      
 0.509
cbl
tRNA-Asn; Codon recognized: AAC.
  
     0.503
Your Current Organism:
Shigella flexneri
NCBI taxonomy Id: 198214
Other names: S. flexneri 2a str. 301, Shigella flexneri 2a str. 301, Shigella flexneri serotype 2a str. 301
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.