STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yihVPutative kinase; Phosphorylates 6-deoxy-6-sulfo-D-fructose (SF) to 6-deoxy-6- sulfo-D-fructose 1-phosphate (SFP); Belongs to the carbohydrate kinase PfkB family. (298 aa)    
Predicted Functional Partners:
yihT
Putative aldolase; Cleaves 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP) to form dihydroxyacetone phosphate (DHAP) and 3-sulfolactaldehyde (SLA). Belongs to the aldolase LacD family.
 
  
 0.798
yihW
Putative DEOR-type transcriptional regulator; Code: KG; COG: COG1349.
  
  
 0.729
rbsD
D-ribose high-affinity transport system; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
 
  
 0.698
yihU
Putative dehydrogenase; Reduces 3-sulfolactaldehyde (SLA) to 2,3-dihydroxypropane 1- sulfonate (DHPS); Belongs to the HIBADH-related family. 3-sulfolactaldehyde reductase subfamily.
 
  
 0.666
yhfQ
Putative kinase; Catalyzes the ATP-dependent phosphorylation of fructoselysine to fructoselysine 6-phosphate. May function in a fructoselysine degradation pathway that allows S.flexneri to grow on fructoselysine or psicoselysine; Belongs to the carbohydrate kinase PfkB family.
  
     0.644
yaaF
Conserved hypothetical protein; Hydrolyzes both purine and pyrimidine ribonucleosides with a broad-substrate specificity.
 
  
 0.560
SF2161
Kinase; Similar to Escherichia coli K12 conserved hypothetical protein gi: 1788416 (335 aa). BLAST with identity of 97% in 335 aa. This CDS contains an in-frame stop codon. The sequence has been checked and is believed to be correct.
  
   
 0.555
yihS
Conserved hypothetical protein; Code: G; COG: COG2942.
     
 0.554
ybeK
Putative tRNA synthetase; Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.
 
  
 0.548
yeiK
Conserved hypothetical protein; Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively. Has a clear preference for cytidine over uridine. Strictly specific for ribonucleosides; Belongs to the IUNH family. RihB subfamily.
 
  
 0.507
Your Current Organism:
Shigella flexneri
NCBI taxonomy Id: 198214
Other names: S. flexneri 2a str. 301, Shigella flexneri 2a str. 301, Shigella flexneri serotype 2a str. 301
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