STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yhgGConserved hypothetical protein; May function as a transcriptional regulator that controls feoABC expression. (78 aa)    
Predicted Functional Partners:
feoB
Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system.
  
 
 0.992
feoA
Ferrous iron transport protein A; Code: P; COG: COG1918.
  
  
 0.959
ycdO
Conserved hypothetical protein; Involved in Fe(2+) uptake. Could be an iron-binding and/or electron-transfer component (By similarity).
      
 0.764
ycdB
Conserved hypothetical protein; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact (By similarity).
      
 0.736
exbD
Enterochelin transporter (uptake); Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
   
  
 0.517
exbB
Enterochelin transporter (uptake); Code: N; COG: COG0811.
      
 0.509
yhgA
Conserved hypothetical protein.
       0.442
Your Current Organism:
Shigella flexneri
NCBI taxonomy Id: 198214
Other names: S. flexneri 2a str. 301, Shigella flexneri 2a str. 301, Shigella flexneri serotype 2a str. 301
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.