node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHN49321.1 | SHN49325.1 | SAMN02745193_00315 | SAMN02745193_00316 | Acetolactate synthase, large subunit. | Acetolactate synthase, small subunit. | 0.999 |
SHN49321.1 | SHN52304.1 | SAMN02745193_00315 | SAMN02745193_00747 | Acetolactate synthase, large subunit. | Branched chain amino acid aminotransferase apoenzyme. | 0.509 |
SHN49321.1 | SHN57483.1 | SAMN02745193_00315 | SAMN02745193_01647 | Acetolactate synthase, large subunit. | Glutamate synthase (NADH) large subunit. | 0.563 |
SHN49321.1 | SHN58921.1 | SAMN02745193_00315 | SAMN02745193_01883 | Acetolactate synthase, large subunit. | Para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase. | 0.742 |
SHN49321.1 | ilvC | SAMN02745193_00315 | SAMN02745193_00317 | Acetolactate synthase, large subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.990 |
SHN49321.1 | ilvD | SAMN02745193_00315 | SAMN02745193_00964 | Acetolactate synthase, large subunit. | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. | 0.946 |
SHN49321.1 | leuA | SAMN02745193_00315 | SAMN02745193_00320 | Acetolactate synthase, large subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.747 |
SHN49321.1 | leuB | SAMN02745193_00315 | SAMN02745193_00739 | Acetolactate synthase, large subunit. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.901 |
SHN49321.1 | leuC | SAMN02745193_00315 | SAMN02745193_02750 | Acetolactate synthase, large subunit. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.747 |
SHN49321.1 | leuD | SAMN02745193_00315 | SAMN02745193_02748 | Acetolactate synthase, large subunit. | 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.818 |
SHN49325.1 | SHN49321.1 | SAMN02745193_00316 | SAMN02745193_00315 | Acetolactate synthase, small subunit. | Acetolactate synthase, large subunit. | 0.999 |
SHN49325.1 | SHN52304.1 | SAMN02745193_00316 | SAMN02745193_00747 | Acetolactate synthase, small subunit. | Branched chain amino acid aminotransferase apoenzyme. | 0.728 |
SHN49325.1 | SHN57483.1 | SAMN02745193_00316 | SAMN02745193_01647 | Acetolactate synthase, small subunit. | Glutamate synthase (NADH) large subunit. | 0.561 |
SHN49325.1 | SHN58921.1 | SAMN02745193_00316 | SAMN02745193_01883 | Acetolactate synthase, small subunit. | Para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase. | 0.802 |
SHN49325.1 | ilvC | SAMN02745193_00316 | SAMN02745193_00317 | Acetolactate synthase, small subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.998 |
SHN49325.1 | ilvD | SAMN02745193_00316 | SAMN02745193_00964 | Acetolactate synthase, small subunit. | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. | 0.878 |
SHN49325.1 | leuA | SAMN02745193_00316 | SAMN02745193_00320 | Acetolactate synthase, small subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.876 |
SHN49325.1 | leuB | SAMN02745193_00316 | SAMN02745193_00739 | Acetolactate synthase, small subunit. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.963 |
SHN49325.1 | leuC | SAMN02745193_00316 | SAMN02745193_02750 | Acetolactate synthase, small subunit. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.901 |
SHN49325.1 | leuD | SAMN02745193_00316 | SAMN02745193_02748 | Acetolactate synthase, small subunit. | 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.916 |