STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemL-2Glutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate. (431 aa)    
Predicted Functional Partners:
AKS39111.1
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.998
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.995
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.978
AKS39112.1
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
  
 0.948
hemL
Glutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway.
  
  
 
0.904
AKS39114.1
Cytochrome C assembly protein.
  
  
 0.795
AKS39109.1
Stage VI sporulation protein D (LysM domain).
       0.599
AKS39108.1
Aminoglycoside phosphotransferase.
       0.596
AKS38013.1
Malonyl CoA-ACP transacylase.
    
 0.571
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.533
Your Current Organism:
Anoxybacillus gonensis
NCBI taxonomy Id: 198467
Other names: A. gonensis, Anoxybacillus gonensis Belduz et al. 2003, Anoxybacillus sp. DT3-1, Anoxybacillus sp. P39, Anoxybacillus sp. P89, NCCB 100040, NCIMB 13933, strain G2
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