STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (220 aa)    
Predicted Functional Partners:
OSZ78339.1
Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.990
ung
uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
 
  
 0.754
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.694
OSZ81703.1
Cobalamin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.657
OSZ79676.1
A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
 
 
0.579
OSZ82444.1
Peptide-methionine (R)-S-oxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.518
OSZ79550.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.517
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
    
 
 0.511
OSZ81749.1
Histidinol-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.495
OSZ79229.1
DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.454
Your Current Organism:
Chitinophagaceae bacterium IBVUCB1
NCBI taxonomy Id: 1985173
Other names: C. bacterium IBVUCB1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.