node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aceE | argS | Dda3937_03098 | Dda3937_01606 | Pyruvate dehydrogenase, decarboxylase component E1, thiamin-binding protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | arginyl-tRNA synthetase; Protein involved in arginine-tRNA ligase activity, ATP binding, aminoacyl-tRNA ligase activity, tRNA aminoacylation for protein translation and arginyl-tRNA aminoacylation. | 0.673 |
aceE | aspS | Dda3937_03098 | Dda3937_01616 | Pyruvate dehydrogenase, decarboxylase component E1, thiamin-binding protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.668 |
aceE | der | Dda3937_03098 | Dda3937_03709 | Pyruvate dehydrogenase, decarboxylase component E1, thiamin-binding protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 50S ribosome associated factor involved in the biogenesis and stability of 50S ribosomal subunits; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.614 |
aceE | gidA | Dda3937_03098 | Dda3937_00154 | Pyruvate dehydrogenase, decarboxylase component E1, thiamin-binding protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Glucose-inhibited cell-division protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.626 |
aceE | mnmE | Dda3937_03098 | Dda3937_01064 | Pyruvate dehydrogenase, decarboxylase component E1, thiamin-binding protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 5-methylaminomethyl-2-thiouridine-synthesizing GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.656 |
aceE | rpoC | Dda3937_03098 | Dda3937_00221 | Pyruvate dehydrogenase, decarboxylase component E1, thiamin-binding protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | RNA polymerase, beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.708 |
aceE | yidC | Dda3937_03098 | Dda3937_01063 | Pyruvate dehydrogenase, decarboxylase component E1, thiamin-binding protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Cytoplasmic insertase into membrane protein, Sec system; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.695 |
argS | aceE | Dda3937_01606 | Dda3937_03098 | arginyl-tRNA synthetase; Protein involved in arginine-tRNA ligase activity, ATP binding, aminoacyl-tRNA ligase activity, tRNA aminoacylation for protein translation and arginyl-tRNA aminoacylation. | Pyruvate dehydrogenase, decarboxylase component E1, thiamin-binding protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.673 |
argS | aspS | Dda3937_01606 | Dda3937_01616 | arginyl-tRNA synthetase; Protein involved in arginine-tRNA ligase activity, ATP binding, aminoacyl-tRNA ligase activity, tRNA aminoacylation for protein translation and arginyl-tRNA aminoacylation. | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.873 |
argS | der | Dda3937_01606 | Dda3937_03709 | arginyl-tRNA synthetase; Protein involved in arginine-tRNA ligase activity, ATP binding, aminoacyl-tRNA ligase activity, tRNA aminoacylation for protein translation and arginyl-tRNA aminoacylation. | 50S ribosome associated factor involved in the biogenesis and stability of 50S ribosomal subunits; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.629 |
argS | gidA | Dda3937_01606 | Dda3937_00154 | arginyl-tRNA synthetase; Protein involved in arginine-tRNA ligase activity, ATP binding, aminoacyl-tRNA ligase activity, tRNA aminoacylation for protein translation and arginyl-tRNA aminoacylation. | Glucose-inhibited cell-division protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.744 |
argS | mnmE | Dda3937_01606 | Dda3937_01064 | arginyl-tRNA synthetase; Protein involved in arginine-tRNA ligase activity, ATP binding, aminoacyl-tRNA ligase activity, tRNA aminoacylation for protein translation and arginyl-tRNA aminoacylation. | 5-methylaminomethyl-2-thiouridine-synthesizing GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.720 |
argS | rnpA | Dda3937_01606 | Dda3937_01061 | arginyl-tRNA synthetase; Protein involved in arginine-tRNA ligase activity, ATP binding, aminoacyl-tRNA ligase activity, tRNA aminoacylation for protein translation and arginyl-tRNA aminoacylation. | Protein C5 component of RNase P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.651 |
argS | rpoC | Dda3937_01606 | Dda3937_00221 | arginyl-tRNA synthetase; Protein involved in arginine-tRNA ligase activity, ATP binding, aminoacyl-tRNA ligase activity, tRNA aminoacylation for protein translation and arginyl-tRNA aminoacylation. | RNA polymerase, beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.812 |
argS | yidC | Dda3937_01606 | Dda3937_01063 | arginyl-tRNA synthetase; Protein involved in arginine-tRNA ligase activity, ATP binding, aminoacyl-tRNA ligase activity, tRNA aminoacylation for protein translation and arginyl-tRNA aminoacylation. | Cytoplasmic insertase into membrane protein, Sec system; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.680 |
aspS | aceE | Dda3937_01616 | Dda3937_03098 | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | Pyruvate dehydrogenase, decarboxylase component E1, thiamin-binding protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.668 |
aspS | argS | Dda3937_01616 | Dda3937_01606 | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | arginyl-tRNA synthetase; Protein involved in arginine-tRNA ligase activity, ATP binding, aminoacyl-tRNA ligase activity, tRNA aminoacylation for protein translation and arginyl-tRNA aminoacylation. | 0.873 |
aspS | der | Dda3937_01616 | Dda3937_03709 | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 50S ribosome associated factor involved in the biogenesis and stability of 50S ribosomal subunits; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.669 |
aspS | gidA | Dda3937_01616 | Dda3937_00154 | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | Glucose-inhibited cell-division protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.726 |
aspS | mnmA | Dda3937_01616 | Dda3937_02085 | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs; Belongs to the MnmA/TRMU family. | 0.543 |