STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rumA23S rRNA (Uracil-5-) -methyltransferase rumA; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. (444 aa)    
Predicted Functional Partners:
relA
GTP pyrophosphokinase / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
     0.828
barA
Hybrid sensory histidine kinase, in two-component regulatory system with UvrY; The sensor-histidine kinase BarA phosphorylates the response regulator UvrY. BarA could monitor some metabolic product that is representative of the prevalent energy status in the medium. The UvrY-BarA two-component regulatory system is also designated ExpA-ExpS in Erwinia carotovora and GacA-GacS in Pseudomonas aeruginosa; Protein involved in transferase activity, transferring phosphorus-containing groups, transmembrane receptor histidine kinase activity, phosphotransferase activity, nitrogenous group as ac [...]
  
    0.655
rsmF
Ribosomal RNA small subunit methyltransferase F; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
 
  
 0.588
mazG
Nucleoside triphosphate pyrophosphohydrolase; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown.
 
     0.540
ypfI
Predicted hydrolase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
   
    0.505
yggH
tRNA (m7G46) methyltransferase, SAM-dependent; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
 
  
 0.477
rlmL
23S rRNA m2G2445 methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.
  
  
 0.476
rsmB
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.473
yfeX
Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown.
 
      0.456
pyrG
CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
    0.426
Your Current Organism:
Dickeya dadantii
NCBI taxonomy Id: 198628
Other names: D. dadantii 3937, Dickeya dadantii 3937, Dickeya dadantii str. 3937, Dickeya dadantii strain 3937, Erwinia chrysanthemi str. 3937, Pectobacterium chrysanthemi str. 3937
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.