STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fadIbeta-ketoacyl-CoA thiolase, anaerobic, subunit; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (447 aa)    
Predicted Functional Partners:
yfcX
Fatty acid oxidation complex subunit alpha; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. Belongs to the enoyl-CoA hydratase/isomerase family. In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
 0.999
fadB
Fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
 0.999
fadE
Medium-long-chain fatty acyl-CoA dehydrogenase; Protein involved in oxidoreductase activity, acting on the CH-CH group of donors, FAD binding, acyl-CoA dehydrogenase activity, fatty acid oxidation, metabolic process and (OBSOLETE) electron transport.
 
 0.983
ADM97142.1
Enoyl-CoA hydratase; Protein involved in (DEPRECATED) molecular function unknown, catalytic activity, (DEPRECATED) biological process unknown and metabolic process.
 
 0.957
fadA
3-ketoacyl-CoA thiolase (thiolase I); Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
  
  
 
0.921
acs
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
 
 0.916
ADM96971.1
Methylmalonate-semialdehyde dehydrogenase; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown.
   
 0.910
nifJ
Protein involved in iron ion binding, oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxidoreductase activity, electron carrier activity, iron-sulfur cluster binding, catalytic activity, thiamin pyrophosphate binding, fermentation and (OBSOLETE) electron transport.
  
 
 0.893
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
    
 0.891
ADM96950.1
Protein involved in electron carrier activity, oxidoreductase activity, iron-sulfur cluster binding, catalytic activity, thiamin pyrophosphate binding, iron ion binding, oxidoreductase activity, acting on the aldehyde or oxo group of donors, tricarboxylic acid cycle, fermentation and (OBSOLETE) electron transport.
  
 
 0.886
Your Current Organism:
Dickeya dadantii
NCBI taxonomy Id: 198628
Other names: D. dadantii 3937, Dickeya dadantii 3937, Dickeya dadantii str. 3937, Dickeya dadantii strain 3937, Erwinia chrysanthemi str. 3937, Pectobacterium chrysanthemi str. 3937
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