STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (361 aa)    
Predicted Functional Partners:
tyrA
Protein involved in chorismate mutase activity, prephenate dehydrogenase activity, tyrosine biosynthetic process, L-phenylalanine biosynthetic process and aromatic amino acid family biosynthetic process.
 
 0.996
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
 
 0.995
pheA
Protein involved in chorismate mutase activity, prephenate dehydratase activity, L-phenylalanine biosynthetic process, tyrosine biosynthetic process and aromatic amino acid family biosynthetic process.
 
 
 0.980
trpG
Anthranilate synthase component II; Protein involved in catalytic activity, ligase activity, anthranilate synthase activity, tryptophan biosynthetic process, biosynthetic process, glutamine metabolic process and metabolic process.
 
 
 0.971
trpE
Protein involved in anthranilate synthase activity, oxo-acid-lyase activity, tryptophan biosynthetic process and biosynthetic process.
 
 
 0.967
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
  
 0.963
ADM96682.1
Chorismate mutase I precursor; Catalyzes the Claisen rearrangement of chorismate to prephenate.
  
 
 0.958
pabB
Aminodeoxychorismate synthase, subunit I; Protein involved in oxo-acid-lyase activity, folic acid biosynthetic process, biosynthetic process and folic acid and derivative biosynthetic process.
 
 
 0.941
pabA
Aminodeoxychorismate synthase, subunit II; Protein involved in anthranilate synthase activity, catalytic activity, ligase activity, folic acid biosynthetic process, metabolic process, biosynthetic process and glutamine metabolic process.
 
 
 0.932
nifJ
Protein involved in iron ion binding, oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxidoreductase activity, electron carrier activity, iron-sulfur cluster binding, catalytic activity, thiamin pyrophosphate binding, fermentation and (OBSOLETE) electron transport.
   
 
 0.932
Your Current Organism:
Dickeya dadantii
NCBI taxonomy Id: 198628
Other names: D. dadantii 3937, Dickeya dadantii 3937, Dickeya dadantii str. 3937, Dickeya dadantii strain 3937, Erwinia chrysanthemi str. 3937, Pectobacterium chrysanthemi str. 3937
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