STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pmrBSensory histidine kinase in two-component regulatory system with BasR; The PmrA-PmrB two-component system responding to acidic pH and iron controls virulence in the plant pathogen Erwinia carotovora ssp. carotovora; Protein involved in two-component sensor activity, ATP binding, protein histidine kinase activity, transferase activity, transferring phosphorus-containing groups, protein modification process, signal transduction, peptidyl-histidine phosphorylation and phosphorylation. (375 aa)    
Predicted Functional Partners:
pmrA
Response regulator of the two-component transcriptional regulatory system (PmrA-PmrB BasR-BasS); Fe(III)-responding signal transduction system; alternative name pmrA in Salmonella; PmrA is phosphorylated by the sensor-histidine kinase PmrB in response to Fe (III) extracellular iron concentration; PmrA confers resistance to Fe(III)-mediated killing; Protein involved in two-component response regulator activity, transcription and regulation of transcription, DNA-dependent.
 
 0.998
phoP
DNA-binding response regulator in two-component regulatory system with PhoQ; PhoP is phosphorylated by the sensor-histidine kinase PhoQ in response to the extracellular Mg2+ concentration; Protein involved in transcription activator activity, two-component response regulator activity and transcription.
 
 
 0.898
tctD
Transcriptional regulatory protein tctD; The signal transduction histidine kinase associated to the response regulator TctD probably corresponds to ID17792; Protein involved in two-component response regulator activity, transcription and regulation of transcription, DNA-dependent.
 
 
 0.856
yjdB
Putative membrane protein; Protein involved in (DEPRECATED) molecular function unknown, sulfuric ester hydrolase activity, ATP binding, ATPase activity, (DEPRECATED) biological process unknown and metabolic process.
  
  
 0.854
cpxR
Transcriptional regulatory protein cpxR; CpxR is phosphorylated by the sensor histidine kinase CpxA in response to envelope stress; Protein involved in transcription activator activity, two-component response regulator activity, transcription and xenobiotic metabolic process.
 
 
 0.827
baeR
BaeR is phosphorylated by the sensor-histidine kinase BaeS in response to envelope stress; Protein involved in two-component response regulator activity, transcription and regulation of transcription, DNA-dependent.
 
 
 0.817
ADM97193.1
Phosphate regulon transcriptional regulatory protein phoB; Protein involved in two-component response regulator activity and transcription.
 
 
 0.811
ADM96448.1
DNA-binding heavy metal response regulator; Protein involved in two-component response regulator activity, regulation of transcription, DNA-dependent and transcription.
 
 
 0.784
ADM97712.1
Phosphate regulon transcriptional regulatory protein phoB; Protein involved in two-component response regulator activity, regulation of transcription, DNA-dependent and transcription.
 
 
 0.783
rstA
DNA-binding response regulator in two-component regulatory system with RstB; Protein involved in two-component response regulator activity, transcription and regulation of transcription, DNA-dependent.
 
 
 0.782
Your Current Organism:
Dickeya dadantii
NCBI taxonomy Id: 198628
Other names: D. dadantii 3937, Dickeya dadantii 3937, Dickeya dadantii str. 3937, Dickeya dadantii strain 3937, Erwinia chrysanthemi str. 3937, Pectobacterium chrysanthemi str. 3937
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