STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
addProtein involved in deaminase activity, adenosine deaminase activity, nucleobase, nucleoside and nucleotide interconversion and purine ribonucleoside monophosphate biosynthetic process; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (338 aa)    
Predicted Functional Partners:
ushA
Protein involved in hydrolase activity, hydrolase activity, acting on ester bonds, nucleotide-sugar biosynthetic process and nucleotide catabolic process; Belongs to the 5'-nucleotidase family.
 
  
 0.926
cpdB
Protein involved in hydrolase activity, 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity, hydrolase activity, acting on ester bonds, nucleobase, nucleoside and nucleotide interconversion, nucleotide catabolic process and nucleotide metabolic process; Belongs to the 5'-nucleotidase family.
    
 0.915
yrfG
Predicted hydrolase; Protein involved in catalytic activity and metabolic process.
   
 0.912
deoD
Protein involved in purine-nucleoside phosphorylase activity, catalytic activity, nucleobase, nucleoside and nucleotide interconversion, nucleobase, nucleoside, nucleotide and nucleic acid metabolic process and nucleoside metabolic process.
    
 0.912
ADM97900.1
Inosine-uridine preferring nucleoside hydrolase; Protein involved in macromolecule catabolic process; Belongs to the IUNH family.
 
 
 0.910
ADM97899.1
Inosine-uridine preferring nucleoside hydrolase; Protein involved in nucleotide-sugar biosynthetic process; Belongs to the IUNH family.
 
 
 0.910
yaiE
Conserved protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
 0.901
acs
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
     
 0.657
tyrS
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
      
 0.616
prfA
Peptide chain release factor RF-1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
     
 0.613
Your Current Organism:
Dickeya dadantii
NCBI taxonomy Id: 198628
Other names: D. dadantii 3937, Dickeya dadantii 3937, Dickeya dadantii str. 3937, Dickeya dadantii strain 3937, Erwinia chrysanthemi str. 3937, Pectobacterium chrysanthemi str. 3937
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.