STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rhsARhs-family protein; Toxic component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. This protein may be a nuclease that is specifically inhibited by its cognate immunity protein RhsAI. Upon expression of the C- terminus (residues 1284-1434) in E.coli growth is inhibited, cells elongate, nucleoids condense and plasmid DNA is degraded; these effects are blocked specifically by cognate immunity protein RshIA. Cell contact is necessary for growth inhibition. (1434 aa)    
Predicted Functional Partners:
ADM97067.1
Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown.
  
 
 0.995
ADM99132.1
Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown.
  
 
 0.980
vgrGA
Putative Rhs accessory genetic element; A Vgr protein that is probably part of a type VI secretion system (T6SS). May be required for export of proteins involved in Rhs- mediated cellular contact-dependent growth inhibition (CDI); Belongs to the VgrG protein family.
 
  
 0.931
rhsIA
Hypothetical protein; Immunity component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. Specifically inhibits its cognate toxin RhsA. Cell contact is necessary for growth inhibition.
     
 0.872
hcpA
Hcp; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown.
 
  
 0.763
vgrGB
Putative Rhs accessory genetic element; A Vgr protein that is probably part of a type VI secretion system (T6SS). May be required for export of proteins involved in Rhs- mediated cellular contact-dependent growth inhibition (CDI); Belongs to the VgrG protein family.
 
  
 0.744
ADM97677.1
ImpB; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown.
 
  
 0.695
ADM97684.1
ImpJ; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown.
 
  
 0.678
ADM97680.1
Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown.
 
  
 0.678
ADM97678.1
Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown.
 
  
 0.650
Your Current Organism:
Dickeya dadantii
NCBI taxonomy Id: 198628
Other names: D. dadantii 3937, Dickeya dadantii 3937, Dickeya dadantii str. 3937, Dickeya dadantii strain 3937, Erwinia chrysanthemi str. 3937, Pectobacterium chrysanthemi str. 3937
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