STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sbcDExonuclease, dsDNA, ATP-dependent; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (410 aa)    
Predicted Functional Partners:
sbcC
Exonuclease, dsDNA, ATP-dependent; Protein involved in ATP binding, DNA catabolic process and DNA metabolic process.
 
 0.998
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.968
ADM97030.1
Possible ATPase involved in DNA repair; Protein involved in (DEPRECATED) molecular function unknown, hydrogen ion transporting ATP synthase activity, rotational mechanism, proton-transporting ATPase activity, rotational mechanism, ATP binding, (DEPRECATED) biological process unknown, ATP biosynthetic process, ATP synthesis coupled proton transport and DNA metabolic process.
  
 0.962
ygdG
Ssb-binding protein; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
  
 0.885
recQ
ATP-dependent DNA helicase; Protein involved in nucleic acid binding, helicase activity, ATP binding, ATP-dependent DNA helicase activity, ATP-dependent helicase activity, DNA repair, DNA-dependent DNA replication, DNA recombination and SOS response.
  
 0.884
recA
DNA strand exchange and recombination protein with protease and nuclease activity; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.762
dinG
ATP-dependent DNA helicase; DNA-dependent ATPase and 5'-3' DNA helicase.
   
 0.740
yoaA
Conserved protein with nucleoside triphosphate hydrolase domain; Protein involved in ATP-dependent DNA helicase activity, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, nucleic acid binding, ATP binding, ATP-dependent helicase activity and nucleobase, nucleoside, nucleotide and nucleic acid metabolic process.
   
 0.740
ychM
Predicted sulphate anion transporter; Protein involved in transporter activity, secondary active sulfate transmembrane transporter activity, transport and sulfate transport.
  
   0.704
ADM97663.1
Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown.
    
  0.667
Your Current Organism:
Dickeya dadantii
NCBI taxonomy Id: 198628
Other names: D. dadantii 3937, Dickeya dadantii 3937, Dickeya dadantii str. 3937, Dickeya dadantii strain 3937, Erwinia chrysanthemi str. 3937, Pectobacterium chrysanthemi str. 3937
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