node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
fabF | holB | Dda3937_02246 | Dda3937_02250 | 3-oxoacyl-[acyl-carrier-protein] synthase, KASII; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | DNA polymerase III, delta prime subunit; Protein involved in DNA-directed DNA polymerase activity, 3'-5' exonuclease activity, DNA-dependent DNA replication and DNA replication. | 0.544 |
fabF | pabC | Dda3937_02246 | Dda3937_02247 | 3-oxoacyl-[acyl-carrier-protein] synthase, KASII; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 4-amino-4-deoxychorismate lyase component of para-aminobenzoate synthase multienzyme complex; Protein involved in catalytic activity, folic acid biosynthetic process and metabolic process. | 0.582 |
fabF | tmk | Dda3937_02246 | Dda3937_02249 | 3-oxoacyl-[acyl-carrier-protein] synthase, KASII; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.561 |
fabF | yceG | Dda3937_02246 | Dda3937_02248 | 3-oxoacyl-[acyl-carrier-protein] synthase, KASII; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | Conserved protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.523 |
fabF | ycfH | Dda3937_02246 | Dda3937_02251 | 3-oxoacyl-[acyl-carrier-protein] synthase, KASII; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | Predicted metallodependent hydrolase; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. | 0.488 |
holB | fabF | Dda3937_02250 | Dda3937_02246 | DNA polymerase III, delta prime subunit; Protein involved in DNA-directed DNA polymerase activity, 3'-5' exonuclease activity, DNA-dependent DNA replication and DNA replication. | 3-oxoacyl-[acyl-carrier-protein] synthase, KASII; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.544 |
holB | pabC | Dda3937_02250 | Dda3937_02247 | DNA polymerase III, delta prime subunit; Protein involved in DNA-directed DNA polymerase activity, 3'-5' exonuclease activity, DNA-dependent DNA replication and DNA replication. | 4-amino-4-deoxychorismate lyase component of para-aminobenzoate synthase multienzyme complex; Protein involved in catalytic activity, folic acid biosynthetic process and metabolic process. | 0.837 |
holB | tmk | Dda3937_02250 | Dda3937_02249 | DNA polymerase III, delta prime subunit; Protein involved in DNA-directed DNA polymerase activity, 3'-5' exonuclease activity, DNA-dependent DNA replication and DNA replication. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.942 |
holB | yceG | Dda3937_02250 | Dda3937_02248 | DNA polymerase III, delta prime subunit; Protein involved in DNA-directed DNA polymerase activity, 3'-5' exonuclease activity, DNA-dependent DNA replication and DNA replication. | Conserved protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.847 |
holB | ycfH | Dda3937_02250 | Dda3937_02251 | DNA polymerase III, delta prime subunit; Protein involved in DNA-directed DNA polymerase activity, 3'-5' exonuclease activity, DNA-dependent DNA replication and DNA replication. | Predicted metallodependent hydrolase; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. | 0.814 |
lepA | metG | Dda3937_03848 | Dda3937_03935 | GTP-binding membrane protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.477 |
lepA | rluC | Dda3937_03848 | Dda3937_04198 | GTP-binding membrane protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.443 |
lepA | ycfH | Dda3937_03848 | Dda3937_02251 | GTP-binding membrane protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Predicted metallodependent hydrolase; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. | 0.488 |
lepA | ygjD | Dda3937_03848 | Dda3937_03531 | GTP-binding membrane protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Predicted peptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.701 |
metG | lepA | Dda3937_03935 | Dda3937_03848 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | GTP-binding membrane protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.477 |
metG | rluC | Dda3937_03935 | Dda3937_04198 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.448 |
metG | tmk | Dda3937_03935 | Dda3937_02249 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.492 |
metG | ycfH | Dda3937_03935 | Dda3937_02251 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Predicted metallodependent hydrolase; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. | 0.449 |
metG | ygjD | Dda3937_03935 | Dda3937_03531 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Predicted peptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.607 |
pabC | fabF | Dda3937_02247 | Dda3937_02246 | 4-amino-4-deoxychorismate lyase component of para-aminobenzoate synthase multienzyme complex; Protein involved in catalytic activity, folic acid biosynthetic process and metabolic process. | 3-oxoacyl-[acyl-carrier-protein] synthase, KASII; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.582 |