STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadRNadR transcriptional repressor / ribosylnicotinamide kinase / NMN adenylyltransferase; NadR is a bifunctional protein that is also involved in the transport of NAD; NadR belongs to the Cro/cI family of transcriptional regulators; Protein involved in transcription repressor activity, DNA binding, transcription regulator activity, catalytic activity, sequence-specific DNA binding, NAD biosynthetic process, transcription, transport, pyridine nucleotide biosynthetic process, regulation of transcription and biosynthetic process. (418 aa)    
Predicted Functional Partners:
cobB
Deacetylase of acetyl-CoA synthetase, NAD-dependent; Protein involved in DNA binding, cobalamin biosynthetic process and regulation of transcription, DNA-dependent; Belongs to the sirtuin family. Class III subfamily.
   
 
 0.991
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
    
 0.948
yfjB
NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.947
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
    
 0.946
ygaD
Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown; Belongs to the CinA family.
    
 0.942
nadC
Quinolinate phosphoribosyltransferase; Protein involved in catalytic activity, NAD biosynthetic process and metabolic process; Belongs to the NadC/ModD family.
     
 0.935
nadD
Nicotinic acid mononucleotide adenylyltransferase, NAD(P)-dependent; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
 0.935
ADM98575.1
Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown.
  
    0.918
yqgE
Predicted protein; Homologous to P. aeruginosa AlgH regulatory protein; Protein involved in transcription and regulation of transcription, DNA-dependent; Belongs to the UPF0301 (AlgH) family.
   
    0.916
sthA
Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
  
  0.912
Your Current Organism:
Dickeya dadantii
NCBI taxonomy Id: 198628
Other names: D. dadantii 3937, Dickeya dadantii 3937, Dickeya dadantii str. 3937, Dickeya dadantii strain 3937, Erwinia chrysanthemi str. 3937, Pectobacterium chrysanthemi str. 3937
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