STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (184 aa)    
Predicted Functional Partners:
guaA
GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP.
  
 0.987
purH
Protein involved in IMP cyclohydrolase activity, phosphoribosylaminoimidazolecarboxamide formyltransferase activity, purine nucleotide biosynthetic process and nucleobase, nucleoside and nucleotide interconversion.
 
 0.959
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.954
ADN00444.1
Adenylosuccinate lyase; Protein involved in catalytic activity, adenylosuccinate lyase activity, metabolic process and purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.943
purB
Adenylosuccinate lyase; Protein involved in catalytic activity, adenylosuccinate lyase activity, purine nucleotide biosynthetic process and purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.943
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 
 0.941
gpt
Guanine-xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
  
 
 0.939
ADM99241.1
Glutamine-hydrolyzing GMP synthase; Protein involved in (DEPRECATED) molecular function unknown, catalytic activity, ligase activity, (DEPRECATED) biological process unknown and glutamine metabolic process.
  
 
 0.926
guaC
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
  
 
 0.926
ADM97960.1
Glutamine amidotransferase, class I; Protein involved in catalytic activity, purine nucleotide biosynthetic process and nucleobase, nucleoside and nucleotide interconversion.
  
 
 0.926
Your Current Organism:
Dickeya dadantii
NCBI taxonomy Id: 198628
Other names: D. dadantii 3937, Dickeya dadantii 3937, Dickeya dadantii str. 3937, Dickeya dadantii strain 3937, Erwinia chrysanthemi str. 3937, Pectobacterium chrysanthemi str. 3937
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