node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
atpI | crl | Dda3937_00152 | Dda3937_00935 | ATP synthase, membrane-bound accesory subunit; Protein involved in ATP synthesis coupled proton transport. | DNA-binding transcriptional regulator; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | 0.737 |
atpI | ilvM | Dda3937_00152 | Dda3937_00249 | ATP synthase, membrane-bound accesory subunit; Protein involved in ATP synthesis coupled proton transport. | Acetolactate synthase II, small subunit. | 0.663 |
atpI | seqA | Dda3937_00152 | Dda3937_01556 | ATP synthase, membrane-bound accesory subunit; Protein involved in ATP synthesis coupled proton transport. | Regulatory protein for replication initiation; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.625 |
atpI | viaA | Dda3937_00152 | Dda3937_00157 | ATP synthase, membrane-bound accesory subunit; Protein involved in ATP synthesis coupled proton transport. | Von Willebrand Factor Type A (VWA) domain-containing protein; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. | 0.756 |
atpI | ycbW | Dda3937_00152 | Dda3937_03515 | ATP synthase, membrane-bound accesory subunit; Protein involved in ATP synthesis coupled proton transport. | Predicted protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ. | 0.749 |
atpI | yciS | Dda3937_00152 | Dda3937_04036 | ATP synthase, membrane-bound accesory subunit; Protein involved in ATP synthesis coupled proton transport. | Conserved inner membrane protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | 0.668 |
atpI | yiiU | Dda3937_00152 | Dda3937_03879 | ATP synthase, membrane-bound accesory subunit; Protein involved in ATP synthesis coupled proton transport. | Conserved protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.418 |
atpI | yrbK | Dda3937_00152 | Dda3937_00685 | ATP synthase, membrane-bound accesory subunit; Protein involved in ATP synthesis coupled proton transport. | Conserved protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.676 |
atpI | ytfK | Dda3937_00152 | Dda3937_00162 | ATP synthase, membrane-bound accesory subunit; Protein involved in ATP synthesis coupled proton transport. | Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. | 0.740 |
crl | atpI | Dda3937_00935 | Dda3937_00152 | DNA-binding transcriptional regulator; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | ATP synthase, membrane-bound accesory subunit; Protein involved in ATP synthesis coupled proton transport. | 0.737 |
crl | ilvM | Dda3937_00935 | Dda3937_00249 | DNA-binding transcriptional regulator; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | Acetolactate synthase II, small subunit. | 0.710 |
crl | seqA | Dda3937_00935 | Dda3937_01556 | DNA-binding transcriptional regulator; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | Regulatory protein for replication initiation; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.620 |
crl | viaA | Dda3937_00935 | Dda3937_00157 | DNA-binding transcriptional regulator; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | Von Willebrand Factor Type A (VWA) domain-containing protein; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. | 0.769 |
crl | ycbW | Dda3937_00935 | Dda3937_03515 | DNA-binding transcriptional regulator; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | Predicted protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ. | 0.764 |
crl | yciS | Dda3937_00935 | Dda3937_04036 | DNA-binding transcriptional regulator; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | Conserved inner membrane protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | 0.736 |
crl | yiiU | Dda3937_00935 | Dda3937_03879 | DNA-binding transcriptional regulator; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | Conserved protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.737 |
crl | yrbK | Dda3937_00935 | Dda3937_00685 | DNA-binding transcriptional regulator; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | Conserved protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.496 |
crl | ytfK | Dda3937_00935 | Dda3937_00162 | DNA-binding transcriptional regulator; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. | 0.774 |
ftsZ | ycbW | Dda3937_02231 | Dda3937_03515 | GTP-binding tubulin-like cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Predicted protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ. | 0.755 |
ilvM | atpI | Dda3937_00249 | Dda3937_00152 | Acetolactate synthase II, small subunit. | ATP synthase, membrane-bound accesory subunit; Protein involved in ATP synthesis coupled proton transport. | 0.663 |