STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pykAPyruvate kinase II; Protein involved in magnesium ion binding, pyruvate kinase activity, potassium ion binding, glycolysis, fermentation and anaerobic respiration; Belongs to the pyruvate kinase family. (480 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
  
 0.983
ADM96950.1
Protein involved in electron carrier activity, oxidoreductase activity, iron-sulfur cluster binding, catalytic activity, thiamin pyrophosphate binding, iron ion binding, oxidoreductase activity, acting on the aldehyde or oxo group of donors, tricarboxylic acid cycle, fermentation and (OBSOLETE) electron transport.
  
 0.965
maeB
Protein involved in malic enzyme activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, NAD binding, acyltransferase activity, metal ion binding, malate metabolic process and metabolic process.
  
 0.965
pgi
Protein involved in glucose-6-phosphate isomerase activity, glycolysis and gluconeogenesis; Belongs to the GPI family.
 
 
 0.962
nifJ
Protein involved in iron ion binding, oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxidoreductase activity, electron carrier activity, iron-sulfur cluster binding, catalytic activity, thiamin pyrophosphate binding, fermentation and (OBSOLETE) electron transport.
  
 0.962
fbaA
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 0.944
sfcA
Malate dehydrogenase, (decarboxylating, NAD-requiring) (malic enzyme); Protein involved in malic enzyme activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, NAD binding, gluconeogenesis and malate metabolic process.
  
 0.938
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
 
 0.936
ldhA
Fermentative D-lactate dehydrogenase, NAD-dependent; Protein involved in oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, NAD binding, cofactor binding, fermentation, lactate oxidation and metabolic process; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.931
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
 
 0.927
Your Current Organism:
Dickeya dadantii
NCBI taxonomy Id: 198628
Other names: D. dadantii 3937, Dickeya dadantii 3937, Dickeya dadantii str. 3937, Dickeya dadantii strain 3937, Erwinia chrysanthemi str. 3937, Pectobacterium chrysanthemi str. 3937
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.