STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepBAminopeptidase B; Probably plays an important role in intracellular peptide degradation. (431 aa)    
Predicted Functional Partners:
pepN
Protein involved in (OBSOLETE) membrane alanyl aminopeptidase activity, zinc ion binding, metallopeptidase activity and proteolysis.
  
 0.924
pepA
Aminopeptidase A, a cyteinylglycinase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
  
  
 
0.922
gshB
Glutathione synthetase; Protein involved in catalytic activity, ATP binding, glutathione synthase activity and glutathione biosynthetic process; Belongs to the prokaryotic GSH synthase family.
   
 
 0.916
ADM99993.1
Putative glutathione synthase; Protein involved in catalytic activity, ATP binding and glutathione biosynthetic process.
   
 
 0.916
pepD
Aminoacyl-histidine dipeptidase (peptidase D); Protein involved in metallopeptidase activity, hydrolase activity, protein dimerization activity, (OBSOLETE) X-His dipeptidase activity and proteolysis.
   
 
 0.915
ggt
Gamma-glutamyltranspeptidase; Protein involved in gamma-glutamyltransferase activity.
     
 0.909
gshA
Protein involved in glutamate-cysteine ligase activity and glutathione biosynthetic process; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
 0.905
chaC
Cation transport protein chaC; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
     
 0.900
aspC
Protein involved in transaminase activity, catalytic activity, transferase activity, transferring nitrogenous groups, pyridoxal phosphate binding, aspartate biosynthetic process, amino acid catabolic process, amino acid metabolic process and biosynthetic process.
    
 0.824
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.823
Your Current Organism:
Dickeya dadantii
NCBI taxonomy Id: 198628
Other names: D. dadantii 3937, Dickeya dadantii 3937, Dickeya dadantii str. 3937, Dickeya dadantii strain 3937, Erwinia chrysanthemi str. 3937, Pectobacterium chrysanthemi str. 3937
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